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  • Dataset: Hexobarbital-Metabolizing Enzyme Induction Study in Mice

    This dataset comes from a study of 100 mice assigned randomly to one of five treatment groups of graded dosages of a drug. They were also given an injection of another drug, and sleeping times were recorded for each mouse. Questions from this study refer to the relationship between sleeping times and dosage. A text file version of the data is found in the relation link.

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  • Dataset: Four Acute Toxicity Studies in Rodents

    This dataset comes from a study of rodents treated with one of 5 or 6 doses of a drug. The proportion of animals that died were recorded. Questions from this study refer to estimating the lethal dosage. A text file version of the data is found in the relation link.

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  • Dataset: Sister Chromatid Exchange (SCE) Study in Mice

    This dataset comes from a study of 10 mice treated with one of 3 doses of a drug. Bone marrow cells were examined and the number of sister chromatid exchanges was recorded for each mouse. Questions from this study refer to the relationship between dosage and chromatid exchange. A text file version of the data is found in the relation link.

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  • Dataset: Alcohol Interaction Study in Men

    This dataset comes from a study of 23 healthy male subjects in a five period crossover study. Each subject followed a randomly allocated sequence of five treatments. Blood samples were collected and serum ethanol levels were recorded. Questions from this study refer to the drug-alcohol interaction. A text file version of the data is found in the relation link.

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  • Dataset: Oral Contraceptive Interaction Study

    This dataset comes from a study of 22 female subjects randomly allocated to 1 of 2 oral contraceptive treatment sequences in a 2 period crossover design. Blood samples were collected at specific time intervals and plasma levels were recorded. Questions from this study refer to the interaction of the two treatments. A text file version of the data is found in the relation link.

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  • Dataset: Cost and Esophageal Healing

    This dataset comes from a study of 184 patients with severe erosive esophagitis were allocated to one of two treatments. Costs and efficacy of the drugs were recorded. Questions from this study refer to differences in cost of the two treatments. A text file version of the data is found in the relation link.

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  • Dataset: Developmental Signs Testing in Rat Pups II

    This dataset comes from a study of female rats allocated to 1 of 4 doses of a drug, and then impregnated by similarly treated males. The pups were tested for developmental signs. Questions from this study refer to the relationship between pup response and dosage. A text file version of the data is found in the relation link.

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  • Dataset: Bioequivalence Study III

    This dataset comes from a study of 16 healthy males allocated to 1 of 2 treatment sequences: wafer/tablet or vice versa. Blood samples were taken and plasma levels were recorded. Questions from this study refer to whether the wafer treatment and the tablet treatment are equivalent. A text file version of the data is found in the relation link.

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  • Dataset: Dose Proportionality Study

    This dataset comes from a study of 16 healthy subjects allocated to 1 of 4 doses of a drug. Blood samples were taken and plasma levels were recorded. Questions from this study refer to the relationship between plasma level and dose. A text file version of the data is found in the relation link.

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  • Dataset: Dose Proportionality Study II

    This dataset comes from a study of 24 healthy subjects allocated to 1 of 4 doses of a drug. Blood samples were taken and plasma levels were recorded. Questions from this study refer to the relationship between plasma level and dose. A text file version of the data is found in the relation link.

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