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  • Dataset: Drug Interaction Study

    This dataset comes from a study of 8 healthy patients randomly assigned to a two-period crossover design. Patients were given 1 of 2 drug sequences and data on blood plasma levels wer recorded. Questions from this study refer how the drugs affect plasma levels. A text file version of the data is found in the relation link.

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  • Dataset: Bioequivalence Study II

    This dataset comes from a study of 26 healthy male subjects randomly assigned to a two-period crossover design. Patients were given either Drug A or Drug B, and data on plasma levels were collected. Questions from this study refer the similarity of the drugs. A text file version of the data is found in the relation link.

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  • Dataset: Method Comparison Study

    This dataset comes from a study of 48 hypertensive patients given one of 3 doses of one drug and one dose of another drug. Questions from this study refer to associations and relationships between the drugs. A text file version of the data is found in the relation link.

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  • Dataset: Combination Therapy Bioequivalence Study

    This dataset comes from a study of 16 healthy subjects randomly assigned to one of two treatment sequences in a two period crossover design. Treatments were from two different drug companies. Questions from this study refer to the similarities of the two treatments. A text file version of the data is found in the relation link.

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  • Dataset: Oral Teratogenic Study in Mice

    This dataset comes from a study of 100 female mice treated with one of 3 doses of a drug, and then impregnated by untreated males. The fetuses were examined for skeletal malformations. Questions from this study refer to the relationship between affected fetuses and dosage. A text file version of the data is found in the relation link.

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  • Dataset: Hexobarbital-Metabolizing Enzyme Induction Study in Mice

    This dataset comes from a study of 100 mice assigned randomly to one of five treatment groups of graded dosages of a drug. They were also given an injection of another drug, and sleeping times were recorded for each mouse. Questions from this study refer to the relationship between sleeping times and dosage. A text file version of the data is found in the relation link.

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  • Dataset: Four Acute Toxicity Studies in Rodents

    This dataset comes from a study of rodents treated with one of 5 or 6 doses of a drug. The proportion of animals that died were recorded. Questions from this study refer to estimating the lethal dosage. A text file version of the data is found in the relation link.

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  • Dataset: Sister Chromatid Exchange (SCE) Study in Mice

    This dataset comes from a study of 10 mice treated with one of 3 doses of a drug. Bone marrow cells were examined and the number of sister chromatid exchanges was recorded for each mouse. Questions from this study refer to the relationship between dosage and chromatid exchange. A text file version of the data is found in the relation link.

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  • Dataset: Alcohol Interaction Study in Men

    This dataset comes from a study of 23 healthy male subjects in a five period crossover study. Each subject followed a randomly allocated sequence of five treatments. Blood samples were collected and serum ethanol levels were recorded. Questions from this study refer to the drug-alcohol interaction. A text file version of the data is found in the relation link.

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  • Dataset: Oral Contraceptive Interaction Study

    This dataset comes from a study of 22 female subjects randomly allocated to 1 of 2 oral contraceptive treatment sequences in a 2 period crossover design. Blood samples were collected at specific time intervals and plasma levels were recorded. Questions from this study refer to the interaction of the two treatments. A text file version of the data is found in the relation link.

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