An Oral Contraceptive Drug Interaction Study.


Authors: 
Bradstreet, T. E., & Panebianco, D. L.
Category: 
Volume: 
12(1)
Pages: 
Online
Year: 
2004
Publisher: 
Journal of Statistics Education
URL: 
http://www.amstat.org/publications/jse/v12n1/datasets.bradstreet.html
Abstract: 

This article focuses on a two treatment, two period, two treatment sequence crossover drug interaction study of a new drug and a standard oral contraceptive therapy. Both normal theory and distribution-free statistical analyses are provided along with a notable amount of graphical insight into the dataset. For one of the variables, the decision on the presence or absence of a drug interaction is reversed depending on whether the normal theory or the distribution-free analysis is favored. The data also contain statistically significant period effects, statistically significant but clinically unimportant treatment effects, some modest degree of structural nonnormality; and modest to more extreme outliers. This and 28 other pedagogically useful datasets can be found at www.math.iup.edu/~tshort/Bradstreet.

The CAUSE Research Group is supported in part by a member initiative grant from the American Statistical Association’s Section on Statistics and Data Science Education

register