A multifactorial scale of attitudes toward statistics was developed, and factors related to attitudes toward statistics (objective and subjective mathematics background, anxiety, spatial ability, expectations, motivation, attitutdes toward computers, teacher and course evaluation, sex and sex-role stereotypes, and major) were investigated for college students in Spain. Regression analyses determined predictors of attitudes toward statistics. Predictive factors before the course included expectations of success and failure; attitudes toward computers; objective and subjective background; motivation; and state anxiety. Predictive factors at the end of the course included: expectations of success and failure; subjective and objective background; level of the subject; and teacher and course evaluation.