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  • Dataset: Bioequivalence Study

    This dataset comes from a study on two treatment sequences (AB, BA) given to 14 healthy male volunteers randomly assigned to a two-period crossover design. Three pharmacokinetic variables were collected on the subjects at the end of each treatment period. Questions this study focused on refer to whether the treatments (A,B)are equivalent. A text file version of the data is found in the relation link.

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  • Dataset: Dose Response/Selection Study in GERD Patients

    This dataset comes from a study on drug treatments of reflux disease patients. Twelve patients were assigned to a four period crossover design, and data on their disease symptoms were collected after treatment. Questions this study focused on refer to dosage of the drug. A text file version of the data is found in the relation link.

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  • Dataset: Exploratory Teratology Study in Rats

    This dataset comes from a study on pregnant rats. Forty rats were given 4 doses of a drug, and data on their fetuses were collected. Questions this study focused on refer to the relationship between dosage of the drug and gender of the fetus. A text file version of the data is found in the relation link.

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  • IDEAL: The Normal Distribution

    This module discusses the history and importance of the normal distribution, as well as normal moments, the standard normal distribution, normal probabilities, Z-Scores, and normal quantiles. The applet allows users to compute normal probabilities and quantiles. Three follow-up examples cover cholesterol, male heights, and mean temperatures for various cities in South Carolina.

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  • Dataset: Swim Maze Testing in Rat Pups

    This dataset comes from a study on rats swimming in a T-shaped maze. Rats were given 4 doses of a drug, and their resulting pups swam the maze until they successfully escaped it 3 consecutive times. Questions from this study refer to the dosage of the drug, the number of swims until 3 consecutive successful escapes, and gender differences. A text file version of the data is found in the relation link.

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  • Dataset: Oral Toxicity Study in Dogs

    This dataset comes from a study on dogs 4 doses of a drug. Data on the alkaline phosphatase levels in their blood was collected throughout the experiment. Questions from this study refer to the relationship between dosage of the drug and alkaline blood levels. A text file version of the data is found in the relation link.

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  • Dataset: Exploratory Pharmacokinetic Study

    This dataset comes from a study of 7 healthy males given a topical medication. Blood samples were collected at specified time intervals, and data on isomer concentrations were collected. Questions from this study refer to the relationship between time and concentration of the isomer. A text file version of the data is found in the relation link.

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  • Dataset: Food Interaction Study

    This dataset comes from a study of 8 healthy males randomly assigned to a two-period crossover design, in which they either fasted and then ate, or ate and then fasted. They were given one dose of a drug, blood samples were collected and data on plasma levels were collected. Questions from this study refer to the absorption of the drug. A text file version of the data is found in the relation link.

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  • Dataset: Pharmacokinetic Study of Carbidopa

    This dataset comes from a study of 12 healthy males randomly assigned to a three-period crossover design, in which were given one of 3 doses of a drug. Blood samples were collected at specified time intervals, and data on plasma levels were collected. Questions from this study refer to the relationship between dosage and plasma levels. A text file version of the data is found in the relation link.

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  • Dataset: Method Comparison Study

    This dataset comes from a study of 48 hypertensive patients given one of 3 doses of one drug and one dose of another drug. Questions from this study refer to associations and relationships between the drugs. A text file version of the data is found in the relation link.

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