{"id":975,"date":"2016-07-19T13:37:49","date_gmt":"2016-07-19T17:37:49","guid":{"rendered":"http:\/\/www.causeweb.org\/tshs\/?p=975"},"modified":"2024-12-11T16:18:27","modified_gmt":"2024-12-11T20:18:27","slug":"tumor-growth","status":"publish","type":"post","link":"https:\/\/causeweb.org\/tshs\/tumor-growth\/","title":{"rendered":"Tumor Growth"},"content":{"rendered":"

Abstract<\/h2>\n\n\n\n

This dataset contains repeated measurements of tumor size from an animal xenograft experiment designed to compare four treatments for cancers. Study animals were n=37 mice with baseline tumor volumes of between40-60 mm3. Animals were assigned to either: 1) control (n=8); drug only (n=10); 3) radiation only (n=10); or 4) drug + radiation (n=9). Tumor size was typically measured on work days for up to four weeks, but the number of repeated measurements is variable because some animals had to be euthanized.<\/p>\n\n\n\n

Study Design<\/th>Topic<\/th>Statistical Method<\/th>Statistical Method<\/th>Statistical Method<\/th><\/tr><\/thead>
Longitudinal<\/td>Tumor Growth<\/td>Linear Mixed Models<\/td>Longitudinal Data<\/td>Repeated Measures<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Contributor<\/h2>\n\n\n\n

The Tumor Growth dataset was contributed by Dr. Constantine Daskalakis, Associate Professor, Thomas Jefferson University. Please refer to this resource as: Constantine Daskalakis, “Tumor Growth Dataset”, TSHS Resources Portal (2016)<\/em>. Available at https:\/\/www.causeweb.org\/tshs\/tumor-growth\/<\/a>.<\/p>\n\n\n\n

Background<\/h2>\n\n\n\n

When basic science research suggests a new possibility for cancer treatment, pre-clinical studies are performed to obtain preliminary assessment in vivo<\/em> of the biological response of human tumors to that treatment. Such translational research often relies on tumor xenograft experiments in animal models.<\/p>\n\n\n\n

Objective<\/h2>\n\n\n\n

The study’s two main specific aims were to assess whether: a) the drug has an effect on tumor growth; and b) the administration of the drug before radiation enhances the effect of the latter on tumor growth.<\/p>\n\n\n\n

Subjects & Variables<\/h2>\n\n\n\n
Subject<\/th># Obs<\/th># Var<\/th>Introduction<\/th>Data Dictionary<\/th><\/tr><\/thead>
Tumor Growth<\/td>574<\/td>4<\/td>Tumor Growth-Introduction<\/a><\/td>Tumor Growth-Data Dictionary<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Data Downloads<\/strong><\/h2>\n\n\n\n
Posting Date<\/th>Contributor (email)<\/th><\/tr><\/thead>
07\/19\/16<\/td>Constantine Daskalakis (constantine.daskalakis@jefferson.edu<\/a>)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
R<\/th>SAS<\/th>STATA<\/th>SPSS<\/th>Minitab<\/th>Excel<\/th><\/tr><\/thead>
Tumor Growth-R<\/a><\/td>Tumor Growth-SAS<\/a><\/td>Tumor Growth-Stata<\/a><\/td>Tumor Growth-SPSS<\/a><\/td>Tumor Growth-Minitab<\/a><\/td>Tumor Growth-Excel<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

top<\/a><\/p>\n\n\n\n

Teaching Resources<\/strong><\/h2>\n\n\n\n

Membership required<\/a><\/p>\n\n\n\n

last updated on 7\/19\/2016<\/em><\/strong><\/p>\n\n\n\n

#<\/th>Name (link)<\/th>Posting Date<\/th>Author (email)<\/th>Type<\/th>Statistical Topic<\/th>Level<\/th>Keywords<\/th><\/tr><\/thead>
1<\/td>Resource 01<\/a><\/td>7\/19\/2016<\/td>Constantine Daskalakis (Constantine.Daskalakis@jefferson.edu<\/a>)<\/td>Lab\/Project<\/td>Inference<\/td>Intro\/Intermediate<\/td>Mixed-Effects Modeling<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

top<\/a><\/p>","protected":false},"excerpt":{"rendered":"

Abstract This dataset contains repeated measurements of tumor size from an animal xenograft experiment designed to compare four treatments for cancers. Study animals were n=37 mice with baseline tumor volumes of between40-60 mm3. Animals were assigned to either: 1) control (n=8); drug only (n=10); 3) radiation only (n=10); or 4) drug + radiation (n=9). Tumor […]<\/p>","protected":false},"author":3,"featured_media":980,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8],"tags":[],"class_list":["post-975","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dataset"],"acf":[],"_links":{"self":[{"href":"https:\/\/causeweb.org\/tshs\/wp-json\/wp\/v2\/posts\/975","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/causeweb.org\/tshs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/causeweb.org\/tshs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/causeweb.org\/tshs\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/causeweb.org\/tshs\/wp-json\/wp\/v2\/comments?post=975"}],"version-history":[{"count":24,"href":"https:\/\/causeweb.org\/tshs\/wp-json\/wp\/v2\/posts\/975\/revisions"}],"predecessor-version":[{"id":1824,"href":"https:\/\/causeweb.org\/tshs\/wp-json\/wp\/v2\/posts\/975\/revisions\/1824"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/causeweb.org\/tshs\/wp-json\/wp\/v2\/media\/980"}],"wp:attachment":[{"href":"https:\/\/causeweb.org\/tshs\/wp-json\/wp\/v2\/media?parent=975"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/causeweb.org\/tshs\/wp-json\/wp\/v2\/categories?post=975"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/causeweb.org\/tshs\/wp-json\/wp\/v2\/tags?post=975"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}